For example, genes with altered expression in the heart of BACHD mice (Hspa1a, P4ha1, Tpd52l2, Basp1, Hadh, Baiap2, Fgf13, Zfp932, Hbp1) were previously characterized to play an important role in HD pathology in other tissues. Here, TPD52L2 is linked to Huntington disease.