We enriched our expression pattern analysis by analyzing microarray data with oncomine and incorporating the expression levels of HMGCR, INSIG1, LDLRAP1 and FASN. Our data showed for the first time that the SREBF1 and the SREBF2 regulated pathways are altered in ovarian cancer with the former exhibiting up-regulation and the latter down-regulation. The gene discussed is HMGCR; the disease is ovarian carcinoma.