Aberrant expression of hnRNPs in cancers have been detected, for example hnRNPA2B1 in breast, pancreatic and gastric cancer, hnRNPB1 in lung cancer, esophagus cancer, leukemia and lymphoma, hnRNPC1/C2 in lung cancer, hnRNPA2B2 in thyroid cancer and hnRNPM4 in lung cancer [38]. Here, HNRNPM is linked to esophageal cancer.