CD44 was upregulated to a similar extent and with identical kinetics on T cells expressing wild-type L-selectin (B6), expressing increased levels of L-selectin (LΔP), or deficient in L-selectin (L-sel−/−); on donor F5 T cells following intraperitoneal vaccNP administration (Figures 3C and 3D) and on endogenously generated influenza-specific CD8+ T cells following i.n. influenza administration (Figure 3E). The gene discussed is SELL; the disease is influenza.