The aim of this study was to investigate the expression of LOX and LOXL enzymes in orthotopic rat prostate tumours and in the tumour-adjacent normal prostate tissue, and how Beta-aminopropionitrile (BAPN) treatment (an irreversible inhibitor of LOX and other LOX-family members’ catalytic activity36, 37, 38, 39, 40, 41) would affect rat prostate tumour growth and metastasis. The gene discussed is LOXL3; the disease is neoplasm.