As found previously, the expression of Lox, Loxl1, Loxl2, and also Loxl4, was significantly higher in the tumour-adjacent non-malignant prostate tissue than in tumour-free vehicle injected control prostate tissue (Fig. 1a), showing that the presence of a tumour can induce the expression of Lox and Loxl in the tumour-bearing organ. The gene discussed is LOXL2; the disease is neoplasm.