The ARRP family, in the present study, carried compound heterozygous CNGA1 mutation c.265delC and c.1537G>A, which resulted in a phenotype of classical RP including night blindness, peripheral visual field loss, attenuated vessels, peripheral bone spicule pigmentation, waxy pallor of the optic disc and peripheral chorioretinal atrophy. The gene discussed is CNGA1; the disease is night blindness.