DROSHA mutations were identified in the DNA of one of six blocks of case no. 51I, in the DNA of two of three blocks of case no. 74I, and in the DNA of two of four specimens from the right side tumor of case no. 262I, but in none of the four specimens from the left side tumor of the same patient (Supplementary Figures S1 and S2). The gene discussed is DROSHA; the disease is neoplasm.