EWSR1 and neoplasm: Thus, Uta Dirksen presented first results from the “EFACT” (EWSR1-FLI1 sequence analysis from ctDNA) study ancillary to the European clinical Ewing sarcoma trials Ewing2008 and Ewing 2012, while Marc Ladanyi presented data based on the MSK-IMPACT program at Memorial Sloan Kettering Cancer Center, which provided proof of principle for detection of circulating tumor (ct) DNA in the plasma preceding clinically overt relapse of Ewing sarcoma.