Three months meal replacement with lyophilised (freeze-dried) foods and advice to residents and carers vs advice alone was investigated in 53 people with severe cognitive impairment [61], reporting improved weight (+2.06 kg vs +0.32 kg, p < 0.05) and serum albumin (3.76 mg/dl vs 1.13 mg/dl, p < 0.05), but no differences in MNA, eating behaviour, cognition or mortality. Here, ALB is linked to Cognitive impairment.