Rvnr 2256, an HERVE element at 6: 89371970 which is relatively complete, has 4 shifts and 4 stops in gag, an open pro, 6 shifts and 7 stops in pol and 4 shifts and 2 stops in env. Yet it is able to encode a tumour antigen, represented by the peptide “ATFLGSLTWK”, immunity to which possibly may cause kidney cancer regression [74]. The gene discussed is ERVW-1; the disease is kidney cancer.