Increase in p-Ezrin and F-Actin in PCa cells was inhibited when cells were pre-treated with 100nM PKC inhibitor (Calphostin C) or 10μM PI3K inhibitor (Wortmannin) 2 hours prior to CXCL16 stimulation (Figure 4). This evidence concerns the gene PRRT2 and posterior cortical atrophy.