Hence, higher CXCR6 expression in PC3 cells and consequent higher capping due to increased αvβ3 integrin expression than in LNCaP cells suggests that differential CXCR6 expression could correlate with differential molecular rearrangements required for PCa cell to disseminate, travel and home at the distant sites. The gene discussed is CXCR6; the disease is posterior cortical atrophy.