Studies from seronegative sex workers in Nairobi, Kenya showed that cervical IgA antibodies played a role in their resistance to infection with HIV [25–28], while another study from highly exposed seronegative women in Cote d’Ivoire, showed that IgG, sIgM and sIgA were present in cervicovaginal lavage fluid and that these antibodies are HIV envelope specific [40]. The gene discussed is CD79A; the disease is infection.