In etiological search of viral hepatitis we found HEV IgM was highly positive (EIAgen HEV IgM, Adaltis, Spain, with 98 percent sensitivity and specificity) with negative anti-HEV IgG and RT-PCR (performed by RT-PCR kit, Qiagen GmbH, Hilden, Germany) for HEV was positive in the serum sample taken on the day of admission. The gene discussed is CD40LG; the disease is viral hepatitis.