The precise role of SIRT2 in tumors is still a matter of debate with some reports showing a correlation between SIRT2 levels and poor prognosis in non-small-cells lung cancer or progression of cervical cancer [136, 137], whereas others report a correlation between low levels of SIRT2 and non-small lung cancer [138]. The gene discussed is SIRT2; the disease is non-small cell lung carcinoma.