SASH1 and cancer: We observed greater within-pair difference in DNA methylation in cancer-discordant twins compared to healthy twins, with nominally significant effects at cg27094856 in AXL (healthy median 0.78 % vs. cancer median 1.44 %, P = 0.047), and near significant effects at cg02444695 near SASH1 (healthy median 1.48 % vs. cancer median 2.32 %, P = 0.091).