The peak genome-wide significant pan-cancer DMP at cg02444695 upstream of the SASH1 tumour suppressor gene, showed consistently higher DNA methylation in the cancer-affected compared to their healthy co-twins, on average 0.7 % (range −0.9 to 3.0 % in normalised unadjusted DNA methylation levels). The gene discussed is SASH1; the disease is neoplasm.