FHIT and non-small cell lung carcinoma: The pooled OR from 7 studies included 722 males and 290 females’ NSCLC, as shown in Fig. 3 (OR = 1.38, 95% CI = 1.02-1.87, p = 0.04), that indicate that FHIT hypermethylation was correlated with sex status in which it is higher in male than in female.