Consistent with this finding, our analyses of additional published datasets (Wei et al, 2009; Russ et al, 2014) confirmed that regions spanning the above TB‐specific DHSs in the mouse genome had only background levels of H3K27me3 in both CD4 and CD8 TN, where these loci are inactive, and showed the same pattern as differentiated Th2 cells (Fig EV1B). The gene discussed is CD8A; the disease is tuberculosis.