TNFSF10 and cervical carcinoma: Chemotherapy, utilizing agents such as cisplatin and doxorubicin, has also been used to treat cervical cancer but with mixed results.3, 4, 5, 6, 7, 8 As researchers and clinicians have worked to move beyond these relatively non-specific and toxic agents, reagents that activate the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated, extrinsic apoptotic pathway have garnered considerable interest owing to their promise in the treatment of several types of tumors.9, 10, 11, 12, 13, 14, 15, 16, 17