IGF2 and cancer: The reduction in cell viability induced by MIR494 has been observed in other cancer types; indeed, several MIR494 targets have been thus far identified which are associated with reduced cellular survival including IGF2 [17], c-KIT [20], HOXA10 [32], CLPTM1L [33], SCGN [34], CXCR4 [35], and c-myc [36].