The 1095 genes with FDR-level of significance in the RNA-Seq analysis included several previously associated with PD, such as SMOX (spermine oxidase; increased in PD) [11], SPR (sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase); increased in PD) [40], DRD3 (dopamine receptor D3; decreased in PD) [41], and SYT11 (Synaptotagmin XI; decreased in PD) [42]. This evidence concerns the gene SPR and Parkinson disease.