IL22 and colitis: In a mouse model of DSS-induced colitis, Zindl et al. demonstrated that depletion of Ly6G/C+ neutrophils/dendritic cells using RB6-8C antibody resulted in reduced colonic levels of IL-22, and additionally, these isolated colonic neutrophils were capable of producing IL-22 after IL-23 stimulation (Zindl et al., 2013).