In relation to muscular dystrophy, important findings of this immunoprecipitation/mass spectrometry study were the demonstration that the dystroglycan subcomplex exhibits a different protein interaction profile in mdx muscles and that overexpression of the synaptic muscle glycosyltransferase Galgt2 can modify α-dystroglycan and thereby counteract dystrophic symptoms [78]. Here, DAG1 is linked to muscular dystrophy.