These studies along with the extensive literature highlighting the importance of adult neurogenesis in AD (see [17–20], for recent comprehensive reviews of this area) prompted our present study in which we have assessed cellular proliferation and neurogenesis in the dentate gyrus (DG) and subventricular zone (SVZ) of both WT and Abca7−/− adult male mice. Here, ABCA7 is linked to Alzheimer disease.