IGHE and allergic rhinitis: Aiming to elucidate the putative association of common gene variants affecting the FcεRI subunits in the clinical presentation and/or in risk of developing allergic rhinitis, we analyzed the association of the variants of FCER1A, FCER1B, FCER1G genes with several clinical phenotype parameters, including IgE levels, in a large group of well-phenotyped allergic rhinitis patients and control individuals; we also analyzed putative gene-gene interactions which, as yet, have not been explored.