In order to identify molecular pathways that drive disease activity in RA synovitis, we calculated the correlation coefficients of clinical disease activity scores (DAS28-CRP, CDAI, SDAI) with the expression levels of 51,452 individual probe sets in 65 synovial biopsies from 33 different RA patients (collected prospectively before and after administration of several therapies; see Table 1). This evidence concerns the gene CRP and rheumatoid arthritis.