EGFR and neoplasm: We found that integrin overexpression could significantly (Student's t-test, P<0.0001) rescue the GSC tumour phenotypes associated with expressing a dominant-negative form of EGFR (EGFRDN; Fig. 7b), rlRNAi (Fig. 7d), zfh-1 (Supplementary Fig. 13e) and hopTum−l (Supplementary Fig. 14a) in somatic cells.