Among these genes, several encode chemokines (IL8, CXCL1, CXCL10, CXCL11, CXCL9, PF4, PPBP), a family of small proteins that play important roles in the immune system through leukocyte recruitment, cell communication and cell activation during infection [55, 56]. The gene discussed is CXCL8; the disease is infection.