Recently, several studies showed that miR-141 inhibited HCC growth, migration, and invasion by targeting the hepatocyte nuclear factor-3β (HNF-3β) [34], T lymphoma invasion and metastasis 1 (Tiam1) [35], and zinc finger E-box binding homeobox 2 (ZEB2) [36]. This evidence concerns the gene ZEB2 and hepatocellular carcinoma.