IFNα and BV6 cooperated to induce apoptosis (determined by DNA fragmentation as a typical marker of apoptotic cell death) and to reduce cell viability (measured by MTT assay) in several cell lines from different cancer entities including HT-29 colon carcinoma, A172 and T98G glioblastoma, BxPC-3 pancreatic carcinoma, RH30 rhabdomyosarcoma and A4573 Ewing sarcoma cells (Figure 1A). The gene discussed is IFNA2; the disease is rhabdomyosarcoma.