Our study results were in agreement with Sugie et al. [28] in a Japanese population, but Wu et al. (Taiwan) [29], Cheng et al. (USA) [30], and Kopp et al. (Denmark) [13] showed the absence of risk association between COX-2 (-1195G>A) polymorphism and prostate cancer risk. The gene discussed is PTGS2; the disease is prostate cancer.