CRP and chronic obstructive pulmonary disease: Serum biomarkers have been mostly explored in COPD for estimating the risks of exacerbation and for long-term monitoring [13], including procalcitonin [14], N-terminal pro-brain natriuretic peptide (NT-ProBNP) and troponin [15] for short-term assessment, and leukocyte number, fibrinogen and CRP in relation to long-term survival [16], as well as blood eosinophil count as biomarker for the response to inhaled steroids [17].