PLAGL1 and neoplasm: When analyzed in depth, the tumor suppressor Plagl1 (Pleomorphic Adenoma Gene-like 1 also known as Zac1 (Zinc Finger Protein Regulating Apoptosis and Cell-cycle Arrest) and Lot1 (Lost on Transformation 1) UniGene Mm.287857; MGI:1100874) was one of the most downregulated genes in the Rybp deficient cells.