FTO and obesity due to melanocortin 4 receptor deficiency: Since then, many studies have confirmed the association between SNPs in intron 1 of FTO and BMI in non-European populations, notable East Asians [9–11], South Asians [12–16], Africans [17], Hispanics [18, 19], and Native Americans [20], clearly demonstrating that the influence of FTO SNPs on obesity is a global trend.