Our results showed a statistically significant decrease in the percentage of peripheral CD4+CD25+ T cells in vitiligo patients (range from 2.9% to 34% of CD4+ T cells with a mean of 11.49%  ± 8.58%) compared to healthy controls (range from 17% to 27% with a mean of 21.20%  ± 3.08%) with P value <0.05 (Figure 2(a)). This evidence concerns the gene CD4 and vitiligo.