In addition, the expression of HERG2, HERG3 and other potentially oncogenic Kv channels such as Kv1.3, KCa3.1 and Kv3.4 was also assessed in a panel of HNSCC-derived cell lines, as well as the contribution of histone acetylation to the regulation of aberrant Kv gene expression in HNSCC. This evidence concerns the gene KCNA3 and head and neck squamous cell carcinoma.