In addition, mean DKK-1 level was significantly higher for patients with than without typical erosions related to RA at baseline (n = 110 vs n = 584) (32.3 ± 14.0 vs 27.2 ± 12.9 pmol/L; P = 0.0001) (Fig. 4). Here, DKK1 is linked to rheumatoid arthritis.