An SNV in MAGEE2 (Fig. 4), which was present in all BD patients but not in HB1, may generate a truncated protein; likewise, the nonsense SNV in NLRP14 encodes a truncated form of the protein (Fig. 2b) that contains only a portion of an important N-terminal domain21. The gene discussed is NLRP14; the disease is Behcet disease.