TP53 and neoplasm: TCD50 (tumor control dose 50%) of xenograft mice was 12.1 Gy, 15.2 Gy, and 19.4 Gy in pE6-R4-p53-EGFP/H1299, pE6-p53-EGFP/H1299, and H1299 (p53-EGFP) group, respectively, and SER (sensitizer enhancement ratio) of pE6-R4-p53-EGFP/H1299 group and pE6-p53-EGFP/H1299 group was 1.6 and 1.28, respectively.