The results from our experiments indicate that the Bax/Bcl-2 and caspase-3/β-actin ratios were significantly decreased at the different time courses of 1, 6, and 18 hours after OLTx in the LR + UTI and LR + UTI + RT groups than in the LR control group, indicating that the mechanisms of UTI in protecting the liver from IRI may occur through upregulating the expression of Bcl-2 and downregulating the expression of Caspase-3. Here, CASP3 is linked to bacterial urinary tract infection.