MUC5AC and cancer: In an attempt to produce a specific antihuman cancer vaccine by combining one of the most specific cancer-associated structures, the Tn antigen (alpha-GalNAC-O-Ser/Thr) with mucin (MUC) 6, it was noted that Tn strongly diminished immunogenicity compared to MUC6 alone via a partial abrogation of Th1 response and promotion of IL-17 responses [34].