Frequencies of CD4+CD25+Foxp3+ T cells in the spleen and PLN were similar in T1D-MSCs (2.27 ± 0.18 % and 0.51 ± 0.21 %), C-MSCs (2.28 ± 0.30 % and 0.43 ± 0.24 %), and control (2.07 ± 0.19 % and 0.51 ± 0.21 %) groups, respectively (Fig. 6). This evidence concerns the gene FOXP3 and type 1 diabetes mellitus.