A 4-point score system has been proposed to identify patients with liver failure at higher risk for poor anticoagulation control and bleeding during warfarin therapy (one point each for albumin [2.5–3.49 g/dL] or creatinine [1.01–1.99 mg/dL], and 2 points each for albumin [<2.5 g/dL] or creatinine [≥2 mg/dL]. The gene discussed is ALB; the disease is Hepatic failure.