Thus, there are the characteristic extraneuronal amyloid-beta plaques and aggregated hyperphosphorylated tau deposits within neurons in Alzheimer's disease (AD); the aggregated α-syn deposits in Lewy Bodies (LBs) which are intraneuronal inclusions, and also within dystrophic neuronal processes called Lewy neurites (LNs) in PD, PD dementia and Dementia with Lewy bodies (DLBs)2-4. The gene discussed is MAPT; the disease is Alzheimer disease.