While Fujii et al.46 described ERBB2 dependency on nuclear YBX1 in breast cancer, another study stated that ERBB2 is not dependent on YBX1 expression in breast cancer.41 Similar to the latter study, no correlation could be determined between YBX1 and ERBB2 in CRC in our cohort. Here, YBX1 is linked to colorectal carcinoma.