Of these, 6 had statistically significant univariate analysis of elevated tumoral MCT4 correlating with decreased DFS in renal cell carcinoma [34], soft tissue sarcoma [35], hepatocellular carcinoma [29, 30], Lacrimal gland adenoid cystic carcinoma [36], non-small-cell lung cancer [42], and glioblastoma multiforme [43]. This evidence concerns the gene SLC16A4 and hereditary clear cell renal cell carcinoma.