BRCA1 and Familial prostate cancer: Cybulski et al. [22] analyzed BRCA1 mutations (C61G, 4153delA, 5382insC) in a large group of 1793 patients with prostate cancer and 4570 population controls and found an association of C61G, 4153delA but not 5382insC with an increased prostate cancer risk (OR = 3.6, p = 0.045).