We have previously analyzed a large panel of melanoma cell lines from the “European Searchable Tumor Cell Line and Data Bank” (ESTDAB, http://www.ebi.ac.uk/ipd/estdab/) and “Outcome and impact of specific treatment in European research on melanoma” (OISTER, QLG1-CT-2002-00668) projects demonstrating a high expression of ligands for NK-cell activating receptors on these cell lines. This evidence concerns the gene NCR1 and melanoma.