It was determined in vitro whether the anti‐EGFR mAb nimotuzumab could suppress phosphorylation of EGFR in human GBM cells overexpressing either EGFRvIII or wtEGFR and the well‐characterized human glioma cell lines U87MG.∆EGFR and U87MG.wtEGFR were used on the experiments 6, 7. This evidence concerns the gene EGFR and glioblastoma.