In the cerebellum, for example, Kv1.1, Kv1.2, and Kvβ2, in the absence of Kv1.4 and Kvβ1, co-localize in the axon terminals of basket cells, as well as some interneurons in the granule cell layer, which may reasonably account for the ataxia phenotype observed in EA1 patients48. This evidence concerns the gene KCNA2 and episodic ataxia type 1.