KCNA1 and episodic ataxia type 1: In the cerebellum, for example, Kv1.1, Kv1.2, and Kvβ2, in the absence of Kv1.4 and Kvβ1, co-localize in the axon terminals of basket cells, as well as some interneurons in the granule cell layer, which may reasonably account for the ataxia phenotype observed in EA1 patients48.