Finally, examination of WNT7A gene expression in the TCGA breast cancer data set demonstrated an increased Wnt7a expression in primary tumours versus matched normal tissue (paired t-test P=0.0098) and that within primary tumours high WNT7A gene expression is significantly associated with basal-like breast cancer (one-way analysis of variance (ANOVA), P<0.0001; Fig. 8f). This evidence concerns the gene WNT7A and breast cancer.